| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DAPP1 (100-273) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DAPP1 |
| Gene ID: |
27071 |
| Uniprot ID: |
DAPP1_HUMAN |
| Immunogen Region: |
100-273 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 100-273 of human DAPP1 (NP_055210.2). |
| Immunogen Sequence: |
SSLKDFVKHFANQPLIGSET GTLMVLKHPYPRKVEEPSIY ESVRVHTAMQTGRTEDDLVP TAPSLGTKEGYLTKQGGLVK TWKTRWFTLHRNELKYFKDQ MSPEPIRILDLTECSAVQFD YSQERVNCFCLVFPFRTFYL CAKTGVEADEWIKILRWKLS QIRKQLNQGEGTIR |
| Tissue Specificity | Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells. |
| Post Translational Modifications | Phosphorylated on tyrosine residues. |
| Function | May act as a B-cell-associated adapter that regulates B-cell antigen receptor (BCR)-signaling downstream of PI3K. |
| Protein Name | Dual Adapter For Phosphotyrosine And 3-Phosphotyrosine And 3-PhosphoinositideHdapp1B Lymphocyte Adapter Protein Bam32B-Cell Adapter Molecule Of 32 Kda |
| Database Links | Reactome: R-HSA-983695 |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane ProteinMembrane-Associated After Cell Stimulation Leading To Its Translocation |
| Alternative Antibody Names | Anti-Dual Adapter For Phosphotyrosine And 3-Phosphotyrosine And 3-Phosphoinositide antibodyAnti-Hdapp1 antibodyAnti-B Lymphocyte Adapter Protein Bam32 antibodyAnti-B-Cell Adapter Molecule Of 32 Kda antibodyAnti-DAPP1 antibodyAnti-BAM32 antibodyAnti-HSPC066 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
