| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DAO (1-347) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:1000-1:5000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DAO |
| Gene ID: |
1610 |
| Uniprot ID: |
OXDA_HUMAN |
| Immunogen Region: |
1-347 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-347 of human DAO (NP_001908.3). |
| Immunogen Sequence: |
MRVVVIGAGVIGLSTALCIH ERYHSVLQPLDIKVYADRFT PLTTTDVAAGLWQPYLSDPN NPQEADWSQQTFDYLLSHVH SPNAENLGLFLISGYNLFHE AIPDPSWKDTVLGFRKLTPR ELDMFPDYGYGWFHTSLILE GKNYLQWLTERLTERGVKFF QRKVESFEEVAREGADVIVN CTGVWAGALQRDPLLQPGRG QIMKVDAPWMKHFILTHDPE RGIYNSPYIIPGTQTVTLG |
| Function | Regulates the level of the neuromodulator D-serine in the brain. Has high activity towards D-DOPA and contributes to dopamine synthesis. Could act as a detoxifying agent which removes D-amino acids accumulated during aging. Acts on a variety of D-amino acids with a preference for those having small hydrophobic side chains followed by those bearing polar, aromatic, and basic groups. Does not act on acidic amino acids. |
| Protein Name | D-Amino-Acid OxidaseDaaoDamoxDao |
| Database Links | Reactome: R-HSA-389661Reactome: R-HSA-9033241 |
| Cellular Localisation | Peroxisome |
| Alternative Antibody Names | Anti-D-Amino-Acid Oxidase antibodyAnti-Daao antibodyAnti-Damox antibodyAnti-Dao antibodyAnti-DAO antibodyAnti-DAMOX antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
