Name: Anti-CYTH1 antibody (1-70) (STJ117546)
SKU: STJ117546
Availability: InStock

Anti-CYTH1 antibody (1-70) (STJ117546)

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STJ117546

$151.88 - $708.08

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Host:	Rabbit
Applications:	WB/IF/ICC/ELISA
Reactivity:	Human/Mouse/Rat
Note:	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality :	Polyclonal
Conjugation:	Unconjugated
Isotype:	IgG
Formulation:	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Purification:	Affinity purification
Concentration:	Lot specific
Dilution Range:	WB:1:200-1:2000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage Instruction:	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol:	CYTH1
Gene ID:	9267
Uniprot ID:	CYH1_HUMAN
Immunogen Region:	1-70
Specificity:	Recombinant fusion protein containing a sequence corresponding to amino acids 1-70 of human CYTH1 (NP_004753.1).
Immunogen Sequence:	MEEDDSYVPSDLTAEERQEL ENIRRRKQELLADIQRLKDE IAEVANEIENLGSTEERKNM QRNKQVAMGR

Tissue Specificity	Ubiquitous.
Post Translational Modifications	Ubiquitinated by SCF(FBXW11) E3 ubiquitin-protein ligase complex. Ubiquitination induces proteasomal degradation.
Function	Promotes guanine-nucleotide exchange on ARF1, ARF5 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization, through regulation of ARF6 activity.
Protein Name	Cytohesin-1 Ph - Sec7 And Coiled-Coil Domain-Containing Protein 1 Sec7 Homolog B2-1
Database Links	Reactome: R-HSA-6811438
Cellular Localisation	Cell Membrane Peripheral Membrane Protein Cytoplasm Cytosol Cell Junction Tight Junction Adherens Junction Colocalized With Tjp1 During Epithelial Polarization
Alternative Antibody Names	Anti-Cytohesin-1 antibody Anti-Ph - Sec7 And Coiled-Coil Domain-Containing Protein 1 antibody Anti-Sec7 Homolog B2-1 antibody Anti-CYTH1 antibody Anti-D17S811E antibody Anti-PSCD1 antibody

Information sourced from Uniprot.org

Anti-CYTH1 antibody (1-70) (STJ117546)

General Information

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