Anti-CXCR2 antibody (445-538) (STJ506203)

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STJ506203-100
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Host: Rabbit
Applications: ELISA/IP/WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-CXCR2 (445-538) is suitable for use in ELISA, Immunoprecipitation and Western Blot research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Contains Tris, HCl/Glycine buffer pH 7.4-7.8, 30% Glycerol and 0.5% BSA, along with cryo-protective agents, Hepes, and long-term preservatives (0.02% Sodium Azide).
Purification: Affinity Purified
Concentration: 0.5-1.5 Mu g/Mu l
Dilution Range: WB: 1:500
ELISA: 1:10, 000
IP: 1:200
Storage Instruction: Store at-20°C for long term storage. Avoid freeze-thaw cycles.
Gene Symbol: Cxcr2
Gene ID: 12765
Uniprot ID: CXCR2_MOUSE
Immunogen Region: 445-538
Immunogen: Synthetic peptide corresponding to amino acids within region 445-538 on mouse C-X-C Chemokine Receptot type 2.
Post Translational Modifications Phosphorylated upon ligand binding.which is required for desensitization.
Function Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2.
Protein Name C-X-C Chemokine Receptor Type 2
Cxc-R2
Cxcr-2
Gro/Mgsa Receptor
High Affinity Interleukin-8 Receptor B
Il-8r B
Cd Antigen Cd182
Database Links Reactome: R-MMU-380108
Reactome: -MMU-418594
Reactome: -MMU-6798695
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-C-X-C Chemokine Receptor Type 2 antibody
Anti-Cxc-R2 antibody
Anti-Cxcr-2 antibody
Anti-Gro/Mgsa Receptor antibody
Anti-High Affinity Interleukin-8 Receptor B antibody
Anti-Il-8r B antibody
Anti-Cd Antigen Cd182 antibody
Anti-Cxcr2 antibody
Anti-Cmkar2 antibody
Anti-Gpcr16 antibody
Anti-Il8rb antibody

Information sourced from Uniprot.org

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