| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit monoclonal antibody anti-Growth-Regulated Alpha Protein (35-107) is suitable for use in Western Blot research applications. |
| Clonality: |
Monoclonal |
| Clone ID: |
S5526RM |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CXCL1 |
| Gene ID: |
2919 |
| Uniprot ID: |
GROA_HUMAN |
| Immunogen Region: |
35-107 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 35-107 of human CXCL1 (NP_001502.1). |
| Immunogen Sequence: |
ASVATELRCQCLQTLQGIHP KNIQSVNVKSPGPHCAQTEV IATLKNGRKACLNPASPIVK KIIEKMLNSDKSN |
| Post Translational Modifications | N-terminal processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. |
| Function | Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. |
| Protein Name | Growth-Regulated Alpha ProteinC-X-C Motif Chemokine 1Gro-Alpha(1-73Melanoma Growth Stimulatory ActivityMgsaNeutrophil-Activating Protein 3Nap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594Reactome: R-HSA-6783783Reactome: R-HSA-6798695 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Growth-Regulated Alpha Protein antibodyAnti-C-X-C Motif Chemokine 1 antibodyAnti-Gro-Alpha(1-73 antibodyAnti-Melanoma Growth Stimulatory Activity antibodyAnti-Mgsa antibodyAnti-Neutrophil-Activating Protein 3 antibodyAnti-Nap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73 antibodyAnti-CXCL1 antibodyAnti-GRO antibodyAnti-GRO1 antibodyAnti-GROA antibodyAnti-MGSA antibodyAnti-SCYB1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
