| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Clone ID : | S5526RM |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.05% Proclin300, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CXCL1 |
| Gene ID: | 2919 |
| Uniprot ID: | GROA_HUMAN |
| Immunogen Region: | 35-107 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 35-107 of human CXCL1 (NP_001502.1). |
| Immunogen Sequence: | ASVATELRCQCLQTLQGIHP KNIQSVNVKSPGPHCAQTEV IATLKNGRKACLNPASPIVK KIIEKMLNSDKSN |
| Post Translational Modifications | N-terminal processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) are produced by proteolytic cleavage after secretion from peripheral blood monocytes. |
| Function | Has chemotactic activity for neutrophils. May play a role in inflammation and exerts its effects on endothelial cells in an autocrine fashion. In vitro, the processed forms GRO-alpha(4-73), GRO-alpha(5-73) and GRO-alpha(6-73) show a 30-fold higher chemotactic activity. |
| Protein Name | Growth-Regulated Alpha Protein C-X-C Motif Chemokine 1 Gro-Alpha(1-73 Melanoma Growth Stimulatory Activity Mgsa Neutrophil-Activating Protein 3 Nap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73 |
| Database Links | Reactome: R-HSA-380108 Reactome: R-HSA-418594 Reactome: R-HSA-6783783 Reactome: R-HSA-6798695 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Growth-Regulated Alpha Protein antibody Anti-C-X-C Motif Chemokine 1 antibody Anti-Gro-Alpha(1-73 antibody Anti-Melanoma Growth Stimulatory Activity antibody Anti-Mgsa antibody Anti-Neutrophil-Activating Protein 3 antibody Anti-Nap-3 Cleaved Into - Gro-Alpha(4-73 - Gro-Alpha(5-73 - Gro-Alpha(6-73 antibody Anti-CXCL1 antibody Anti-GRO antibody Anti-GRO1 antibody Anti-GROA antibody Anti-MGSA antibody Anti-SCYB1 antibody |
Information sourced from Uniprot.org