Anti-CTU2 antibody (186-515) (STJ114972)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CTU2 (186-515) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CTU2 |
| Gene ID | 348180 |
| Uniprot ID | CTU2_HUMAN |
| Immunogen Region | 186-515 |
| Immunogen Sequence | HVLGAGGGPGPTQGEEQPPQ PPLDPQNLARPPAPAQTEAL SQLFCSVRTLTAKEELLQTL RTHLILHMARAHGYSKVMTG DSCTRLAIKLMTNLALGRGA FLAWDTGFSDERHGDVVVVR PMRDHTLKEVAFYNRLFSVP SVFTPAVDTKAPEKASIHRL MEAFILRLQTQFPSTVSTVY RTSEKLVKGPRDGPAAGDSG PRCLLCMCALDVDAADSATA FGAQTSSRLSQMQSPIPLT |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 186-515 of human CTU2 (NP_001012777.1). |
Additional Info
| Function | Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. |
| Protein Name | Cytoplasmic Trna 2-Thiolation Protein 2Cytosolic Thiouridylase Subunit 2 |
| Database Links | Reactome: R-HSA-6782315 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Cytoplasmic Trna 2-Thiolation Protein 2 antibodyAnti-Cytosolic Thiouridylase Subunit 2 antibodyAnti-CTU2 antibodyAnti-C16orf84 antibodyAnti-NCS2 antibody |
Information sourced from Uniprot.org