| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CTU2 (186-515) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CTU2 |
| Gene ID: |
348180 |
| Uniprot ID: |
CTU2_HUMAN |
| Immunogen Region: |
186-515 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 186-515 of human CTU2 (NP_001012777.1). |
| Immunogen Sequence: |
HVLGAGGGPGPTQGEEQPPQ PPLDPQNLARPPAPAQTEAL SQLFCSVRTLTAKEELLQTL RTHLILHMARAHGYSKVMTG DSCTRLAIKLMTNLALGRGA FLAWDTGFSDERHGDVVVVR PMRDHTLKEVAFYNRLFSVP SVFTPAVDTKAPEKASIHRL MEAFILRLQTQFPSTVSTVY RTSEKLVKGPRDGPAAGDSG PRCLLCMCALDVDAADSATA FGAQTSSRLSQMQSPIPLT |
| Function | Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with CTU1/ATPBD3 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. |
| Protein Name | Cytoplasmic Trna 2-Thiolation Protein 2Cytosolic Thiouridylase Subunit 2 |
| Database Links | Reactome: R-HSA-6782315 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Cytoplasmic Trna 2-Thiolation Protein 2 antibodyAnti-Cytosolic Thiouridylase Subunit 2 antibodyAnti-CTU2 antibodyAnti-C16orf84 antibodyAnti-NCS2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
