Anti-CTNNBL1 antibody (264-563) (STJ28655)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CTNNBL1 (264-563) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CTNNBL1 |
| Gene ID | 56259 |
| Uniprot ID | CTBL1_HUMAN |
| Immunogen Region | 264-563 |
| Immunogen Sequence | EVLAILLQDNDENRELLGEL DGIDVLLQQLSVFKRHNPST AEEQEMMENLFDSLCSCLML SSNRERFLKGEGLQLMNLML REKKISRSSALKVLDHAMIG PEGTDNCHKFVDILGLRTIF PLFMKSPRKIKKVGTTEKEH EEHVCSILASLLRNLRGQQR TRLLNKFTENDSEKVDRLME LHFKYLGAMQVADKKIEGEK HDMVRRGEIIDNDTEEEFYL RRLDAGLFVLQHICYIMAE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 264-563 of human CTNNBL1 (NP_110517.2). |
Additional Info
| Tissue Specificity | Widely expressed with highest levels in skeletal muscle, placenta, heart, spleen, testis and thyroid. |
| Function | Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated somatic hypermutation (SHM) and class-switch recombination (CSR), 2 processes resulting in the production of high-affinity, mutated isotype-switched antibodies. |
| Protein Name | Beta-Catenin-Like Protein 1Nuclear-Associated ProteinNapTestis Development Protein Nyd-Sp19 |
| Database Links | Reactome: R-HSA-72163 |
| Cellular Localisation | Isoform 1: NucleusIsoform 2: Cytoplasm |
| Alternative Antibody Names | Anti-Beta-Catenin-Like Protein 1 antibodyAnti-Nuclear-Associated Protein antibodyAnti-Nap antibodyAnti-Testis Development Protein Nyd-Sp19 antibodyAnti-CTNNBL1 antibodyAnti-C20orf33 antibodyAnti-PP8304 antibody |
Information sourced from Uniprot.org