Host: |
Rabbit |
Applications: |
WB/IF |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-CTNNBL1 (264-563) is suitable for use in Western Blot and Immunofluorescence research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CTNNBL1 |
Gene ID: |
56259 |
Uniprot ID: |
CTBL1_HUMAN |
Immunogen Region: |
264-563 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 264-563 of human CTNNBL1 (NP_110517.2). |
Immunogen Sequence: |
EVLAILLQDNDENRELLGEL DGIDVLLQQLSVFKRHNPST AEEQEMMENLFDSLCSCLML SSNRERFLKGEGLQLMNLML REKKISRSSALKVLDHAMIG PEGTDNCHKFVDILGLRTIF PLFMKSPRKIKKVGTTEKEH EEHVCSILASLLRNLRGQQR TRLLNKFTENDSEKVDRLME LHFKYLGAMQVADKKIEGEK HDMVRRGEIIDNDTEEEFYL RRLDAGLFVLQHICYIMAE |
Tissue Specificity | Widely expressed with highest levels in skeletal muscle, placenta, heart, spleen, testis and thyroid. |
Function | Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. Participates in AID/AICDA-mediated somatic hypermutation (SHM) and class-switch recombination (CSR), 2 processes resulting in the production of high-affinity, mutated isotype-switched antibodies. |
Protein Name | Beta-Catenin-Like Protein 1Nuclear-Associated ProteinNapTestis Development Protein Nyd-Sp19 |
Database Links | Reactome: R-HSA-72163 |
Cellular Localisation | Isoform 1: NucleusIsoform 2: Cytoplasm |
Alternative Antibody Names | Anti-Beta-Catenin-Like Protein 1 antibodyAnti-Nuclear-Associated Protein antibodyAnti-Nap antibodyAnti-Testis Development Protein Nyd-Sp19 antibodyAnti-CTNNBL1 antibodyAnti-C20orf33 antibodyAnti-PP8304 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance