Anti-CRPPA antibody (301-351 aa) (STJ195764)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human ISPD at the amino acid range 301-351
General Information
| Short Description | Rabbit polyclonal anti-D-ribitol-5-phosphate cytidylyltransferase (301-351 aa) for use in WB, ELISA and IHC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA/IHC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CRPPA |
| Gene ID | 729920 |
| Uniprot ID | ISPD_HUMAN |
| Immunogen | Synthesized peptide derived from the human ISPD at the amino acid range 301-351 |
| Immunogen Region | 301-351 aa |
| Specificity | This antibody detects endogenous levels of ISPD at Human/Mouse/Rat |
Additional Info
| Function | Cytidylyltransferase required for protein O-linked mannosylation. Catalyzes the formation of CDP-ribitol nucleotide sugar from D-ribitol 5-phosphate. CDP-ribitol is a substrate of FKTN during the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Shows activity toward other pentose phosphate sugars and mediates formation of CDP-ribulose or CDP-ribose using CTP and ribulose-5-phosphate or ribose-5-phosphate, respectively. Not Involved in dolichol production. |
| Protein Name | D-Ribitol-5-Phosphate Cytidylyltransferase2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase-Like ProteinIsoprenoid Synthase Domain-Containing ProteinHispd |
| Database Links | |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-D-Ribitol-5-Phosphate Cytidylyltransferase antibodyAnti-2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase-Like Protein antibodyAnti-Isoprenoid Synthase Domain-Containing Protein antibodyAnti-Hispd antibodyAnti-CRPPA antibodyAnti-ISPD antibody |
Information sourced from Uniprot.org