| Host: |
Rabbit |
| Applications: |
WB/ELISA/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-D-ribitol-5-phosphate cytidylyltransferase (301-351 aa) is suitable for use in Western Blot, ELISA and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000IHC-P 1:50-300ELISA 2000-20000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CRPPA |
| Gene ID: |
729920 |
| Uniprot ID: |
ISPD_HUMAN |
| Immunogen Region: |
301-351 aa |
| Specificity: |
This antibody detects endogenous levels of ISPD at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human ISPD at the amino acid range 301-351 |
| Function | Cytidylyltransferase required for protein O-linked mannosylation. Catalyzes the formation of CDP-ribitol nucleotide sugar from D-ribitol 5-phosphate. CDP-ribitol is a substrate of FKTN during the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N-acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate-6-)mannose), a carbohydrate structure present in alpha-dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. Shows activity toward other pentose phosphate sugars and mediates formation of CDP-ribulose or CDP-ribose using CTP and ribulose-5-phosphate or ribose-5-phosphate, respectively. Not Involved in dolichol production. |
| Protein Name | D-Ribitol-5-Phosphate Cytidylyltransferase2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase-Like ProteinIsoprenoid Synthase Domain-Containing ProteinHispd |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Antibody Names | Anti-D-Ribitol-5-Phosphate Cytidylyltransferase antibodyAnti-2-C-Methyl-D-Erythritol 4-Phosphate Cytidylyltransferase-Like Protein antibodyAnti-Isoprenoid Synthase Domain-Containing Protein antibodyAnti-Hispd antibodyAnti-CRPPA antibodyAnti-ISPD antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
