Anti-CRP antibody (125-224) [S1MR] (STJ11101541)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal CRP (125-224) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S1MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:2000IHC-P:1:200-1:800ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CRP |
| Gene ID | 1401 |
| Uniprot ID | CRP_HUMAN |
| Immunogen Region | 125-224 |
| Immunogen Sequence | VEFWVDGKPRVRKSLKKGYT VGAEASIILGQEQDSFGGNF EGSQSLVGDIGNVNMWDFVL SPDEINTIYLGGPFSPNVLN WRALKYEVQGEVFTKPQLWP |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 125-224 of human C-Reactive Protein (CRP) (P02741). |
Additional Info
| Tissue Specificity | Found in plasma. |
| Function | Displays several functions associated with host defense: it promotes agglutination, bacterial capsular swelling, phagocytosis and complement fixation through its calcium-dependent binding to phosphorylcholine. Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. |
| Protein Name | C-Reactive Protein Cleaved Into - C-Reactive Protein(1-205 |
| Database Links | Reactome: R-HSA-173623 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-Reactive Protein Cleaved Into - C-Reactive Protein(1-205 antibodyAnti-CRP antibodyAnti-PTX1 antibody |
Information sourced from Uniprot.org