Anti-CRMP4 antibody [R06-5P6] (STJA0037332)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human CRMP4
General Information
| Short Description | Rabbit monoclonal anti-CRMP4 for use in WB, ICC, IF and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF/IP |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-5P6 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IF 1:50-1:200IP 1:50 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | DPYSL3 |
| Gene ID | 1809 |
| Uniprot ID | DPYL3_HUMAN |
| Immunogen | A synthesized peptide derived from human CRMP4 |
Additional Info
| Tissue Specificity | Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord. |
| Post Translational Modifications | Phosphorylation on Ser-522 by DYRK2 promotes subsequent phosphorylation on Thr-509, Thr-514 and Ser-518 by GSK3. |
| Function | Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration. |
| Protein Name | Dihydropyrimidinase-Related Protein 3Drp-3Collapsin Response Mediator Protein 4Crmp-4Unc-33-Like Phosphoprotein 1Ulip-1 |
| Database Links | Reactome: R-HSA-399956 |
| Cellular Localisation | CytoplasmCell ProjectionGrowth ConeColocalizes With Synaptic Vesicle Protein 2 In The Central Region Of The Growth Cone |
| Alternative Antibody Names | Anti-Dihydropyrimidinase-Related Protein 3 antibodyAnti-Drp-3 antibodyAnti-Collapsin Response Mediator Protein 4 antibodyAnti-Crmp-4 antibodyAnti-Unc-33-Like Phosphoprotein 1 antibodyAnti-Ulip-1 antibodyAnti-DPYSL3 antibodyAnti-CRMP4 antibodyAnti-DRP3 antibodyAnti-ULIP antibodyAnti-ULIP1 antibody |
Information sourced from Uniprot.org