Anti-CRMP4 antibody [R06-5P6] (STJA0037332)

SKU:
STJA0037332
£133.50 - £281.50
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Host: Rabbit
Applications: WB/ICC/IF/IP
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit monoclonal anti-CRMP4 for use in WB, ICC, IF and IP in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents.
Clonality : Monoclonal
Clone ID : R06-5P6
Conjugation: Unconjugated
Isotype: IgG
Formulation: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification: Affinity Purified
Dilution Range: WB 1:500-1:1000
IF 1:50-1:200
IP 1:50
Storage Instruction: Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles.
Gene Symbol: DPYSL3
Gene ID: 1809
Uniprot ID: DPYL3_HUMAN
Immunogen: A synthesized peptide derived from human CRMP4
Tissue Specificity Mainly expressed in heart and skeletal muscle. Also strongly expressed in fetal brain and spinal cord.
Post Translational Modifications Phosphorylation on Ser-522 by DYRK2 promotes subsequent phosphorylation on Thr-509, Thr-514 and Ser-518 by GSK3.
Function Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration.
Protein Name Dihydropyrimidinase-Related Protein 3
Drp-3
Collapsin Response Mediator Protein 4
Crmp-4
Unc-33-Like Phosphoprotein 1
Ulip-1
Database Links Reactome: R-HSA-399956
Cellular Localisation Cytoplasm
Cell Projection
Growth Cone
Colocalizes With Synaptic Vesicle Protein 2 In The Central Region Of The Growth Cone
Alternative Antibody Names Anti-Dihydropyrimidinase-Related Protein 3 antibody
Anti-Drp-3 antibody
Anti-Collapsin Response Mediator Protein 4 antibody
Anti-Crmp-4 antibody
Anti-Unc-33-Like Phosphoprotein 1 antibody
Anti-Ulip-1 antibody
Anti-DPYSL3 antibody
Anti-CRMP4 antibody
Anti-DRP3 antibody
Anti-ULIP antibody
Anti-ULIP1 antibody

Information sourced from Uniprot.org