Anti-CRLS1 antibody (1-110) (STJ114266)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CRLS1 (1-110) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:500ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CRLS1 |
| Gene ID | 54675 |
| Uniprot ID | CRLS1_HUMAN |
| Immunogen Region | 1-110 |
| Immunogen Sequence | MLALRVARGSWGALRGAAWA PGTRPSKRRACWALLPPVPC CLGCLAERWRLRPAALGLRL PGIGQRNHCSGAGKAAPRPA AGAGAAAEAPGGQWGPASTP SLYENPWTIP |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-110 of human CRLS1 (NP_061968.1). |
Additional Info
| Tissue Specificity | Highly expressed in tissues such as heart, skeletal muscle and liver. |
| Function | Catalyzes the synthesis of cardiolipin (CL) (diphosphatidylglycerol) by specifically transferring a phosphatidyl group from CDP-diacylglycerol to phosphatidylglycerol (PG). CL is a key phospholipid in mitochondrial membranes and plays important roles in maintaining the functional integrity and dynamics of mitochondria under both optimal and stress conditions. |
| Protein Name | Cardiolipin SynthaseCmp-FormingClsProtein Gcd10 Homolog |
| Database Links | Reactome: R-HSA-1482925Reactome: R-HSA-1483076 |
| Cellular Localisation | Mitochondrion Inner MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Cardiolipin Synthase antibodyAnti-Cmp-Forming antibodyAnti-Cls antibodyAnti-Protein Gcd10 Homolog antibodyAnti-CRLS1 antibodyAnti-C20orf155 antibodyAnti-CLS1 antibody |
Information sourced from Uniprot.org