| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CRLF2 (23-231) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:1000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CRLF2 |
| Gene ID: |
64109 |
| Uniprot ID: |
CRLF2_HUMAN |
| Immunogen Region: |
23-231 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 23-231 of human CRLF2 (NP_071431.2). |
| Immunogen Sequence: |
QGGAAEGVQIQIIYFNLETV QVTWNASKYSRTNLTFHYRF NGDEAYDQCTNYLLQEGHTS GCLLDAEQRDDILYFSIRNG THPVFTASRWMVYYLKPSSP KHVRFSWHQDAVTVTCSDLS YGDLLYEVQYRSPFDTEWQS KQENTCNVTIEGLDAEKCYS FWVRVKAMEDVYGPDTYPSD WSEVTCWQRGEIRDACAETP TPPKPKLSK |
| Tissue Specificity | Expressed in heart, skeletal muscle, kidney and adult and fetal liver. Primarily expressed in dendrites and monocytes. Weakly expressed in T-cells. |
| Function | Receptor for thymic stromal lymphopoietin (TSLP). Forms a functional complex with TSLP and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. Also activates JAK2. Implicated in the development of the hematopoietic system. |
| Protein Name | Cytokine Receptor-Like Factor 2Cytokine Receptor-Like 2Il-XrThymic Stromal Lymphopoietin Protein ReceptorTslp Receptor |
| Database Links | Reactome: R-HSA-1266695 |
| Cellular Localisation | Isoform 1: Cell MembraneSingle-Pass Type I Membrane ProteinIsoform 2: Secreted |
| Alternative Antibody Names | Anti-Cytokine Receptor-Like Factor 2 antibodyAnti-Cytokine Receptor-Like 2 antibodyAnti-Il-Xr antibodyAnti-Thymic Stromal Lymphopoietin Protein Receptor antibodyAnti-Tslp Receptor antibodyAnti-CRLF2 antibodyAnti-CRL2 antibodyAnti-ILXR antibodyAnti-TSLPR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
