Anti-CRHR2 antibody (71-120 aa) (STJ92475)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CRHR2 at the amino acid range 71-120
General Information
| Short Description | Rabbit polyclonal anti-Corticotropin-releasing factor receptor 2 (71-120 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CRHR2 |
| Gene ID | 1395 |
| Uniprot ID | CRFR2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CRHR2 at the amino acid range 71-120 |
| Immunogen Region | 71-120 aa |
| Specificity | CRF-RII Polyclonal Antibody detects endogenous levels of CRF-RII protein. |
Additional Info
| Function | G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels. |
| Protein Name | Corticotropin-Releasing Factor Receptor 2Crf-R-2Crf-R2Crfr-2Corticotropin-Releasing Hormone Receptor 2Crh-R-2Crh-R2 |
| Database Links | Reactome: R-HSA-373080Reactome: R-HSA-418555Reactome: R-HSA-422085 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Corticotropin-Releasing Factor Receptor 2 antibodyAnti-Crf-R-2 antibodyAnti-Crf-R2 antibodyAnti-Crfr-2 antibodyAnti-Corticotropin-Releasing Hormone Receptor 2 antibodyAnti-Crh-R-2 antibodyAnti-Crh-R2 antibodyAnti-CRHR2 antibodyAnti-CRF2R antibodyAnti-CRH2R antibody |
Information sourced from Uniprot.org