![Anti-CRASH antibody [7B6] (STJ16101068)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149784/302533/STJ16101068_1__50559.1646940691.jpg?c=1 "Anti-CRASH antibody [7B6] (STJ16101068)")
![Anti-CRASH antibody [7B6] (STJ16101068)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/149784/302534/STJ16101068_2__11396.1646940691.jpg?c=1 "Anti-CRASH antibody [7B6] (STJ16101068)")
![Anti-CRASH antibody [7B6] (STJ16101068)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/149784/302533/STJ16101068_1__50559.1646940691.jpg?c=1 "Anti-CRASH antibody [7B6] (STJ16101068)")
Anti-CRASH antibody [7B6] (STJ16101068)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenA BALB/c mouse was immunized with CRASH recombinant protein and synthetic peptide. Fusion partner: SP2/0.
General Information
| Short Description | Mouse monoclonal anti-CRASH for use in ELISA, WB and IHC in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/IHC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 7B6 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Concentration | Can be provided as 100 ยตg/mL, 500 ยตg/mL or 1mg/mL. |
| Purification | Affinity purified from tissue culture. |
| Dilution Range | ELISA (solid phase: 0, 1-100 ยตg/ml; tracer: 0, 001-100 ยตg/ml for 30 min at RT). Immunoblotting (1-2 ยตg/ml). Immunohistology (formalin-fixed: 1-2 ยตg/ml for 30 min at RT; staining of formalin-fixed tissues requires boiling tissue sections in 10mM Citra |
| Formulation | PBS with 0.02% Sodium Azide. |
| Storage Instruction | Store for up to 1 year at 2-8ยฐC upon receipt. |
Target Information
| Gene Symbol | ASRGL1 |
| Gene ID | 80150 |
| Uniprot ID | ASGL1_HUMAN |
| Immunogen | A BALB/c mouse was immunized with CRASH recombinant protein and synthetic peptide. Fusion partner: SP2/0. |
Additional Info
| Tissue Specificity | Expressed in brain, kidney, testis and tissues of the gastrointestinal tract. Present in sperm (at protein level). Over-expressed in uterine, mammary, prostatic and ovarian carcinoma. |
| Post Translational Modifications | Cleaved into an alpha and beta chain by autocatalysis.this activates the enzyme. The N-terminal residue of the beta subunit is responsible for the nucleophile hydrolase activity. |
| Function | Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine. |
| Protein Name | Isoaspartyl Peptidase/L-AsparaginaseAsparaginase-Like Protein 1Beta-Aspartyl-PeptidaseIsoaspartyl DipeptidaseL-Asparagine Amidohydrolase Cleaved Into - Isoaspartyl Peptidase/L-Asparaginase Alpha Chain - Isoaspartyl Peptidase/L-Asparaginase Beta Chain |
| Database Links | Reactome: R-HSA-8964208 |
| Cellular Localisation | CytoplasmMidpiece Of Sperm Tail |
| Alternative Antibody Names | Anti-Isoaspartyl Peptidase/L-Asparaginase antibodyAnti-Asparaginase-Like Protein 1 antibodyAnti-Beta-Aspartyl-Peptidase antibodyAnti-Isoaspartyl Dipeptidase antibodyAnti-L-Asparagine Amidohydrolase Cleaved Into - Isoaspartyl Peptidase/L-Asparaginase Alpha Chain - Isoaspartyl Peptidase/L-Asparaginase Beta Chain antibodyAnti-ASRGL1 antibodyAnti-ALP antibodyAnti-CRASH antibody |
Information sourced from Uniprot.org