| Host: | Rabbit |
| Applications: | WB/IF/ICC/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IF/ICC:1:20-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CRABP2 |
| Gene ID: | 1382 |
| Uniprot ID: | RABP2_HUMAN |
| Immunogen Region: | 22-94 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-94 of human CRABP2 (NP_001869.1). |
| Immunogen Sequence: | VLGVNVMLRKIAVAAASKPA VEIKQEGDTFYIKTSTTVRT TEINFKVGEEFEEQTVDGRP CKSLVKWESENKM |
| Post Translational Modifications | Sumoylated in response to retinoic acid binding, sumoylation is critical for dissociation from ER and subsequent nuclear translocation. |
| Function | Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors. |
| Protein Name | Cellular Retinoic Acid-Binding Protein 2Cellular Retinoic Acid-Binding Protein IiCrabp-Ii |
| Database Links | Reactome: R-HSA-5362517 |
| Cellular Localisation | CytoplasmEndoplasmic ReticulumNucleusUpon Ligand BindingA Conformation Change Exposes A Nuclear Localization Motif And The Protein Is Transported Into The Nucleus |
| Alternative Antibody Names | Anti-Cellular Retinoic Acid-Binding Protein 2 antibodyAnti-Cellular Retinoic Acid-Binding Protein Ii antibodyAnti-Crabp-Ii antibodyAnti-CRABP2 antibody |
Information sourced from Uniprot.org