Anti-CPT2 antibody (420-658) (STJ23216)

Name: Anti-CPT2 antibody (420-658) (STJ23216)
SKU: STJ23216
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ23216

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Short Description	Rabbit polyclonal CPT2 (420-658) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:100-1:500 IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	CPT2
Gene ID	1376
Uniprot ID	CPT2_HUMAN
Immunogen Region	420-658
Immunogen Sequence	TDALKTGITAAKEKFDATMK TLTIDCVQFQRGGKEFLKKQ KLSPDAVAQLAFQMAFLRQY GQTVATYESCSTAAFKHGRT ETIRPASVYTKRCSEAFVRE PSRHSAGELQQMMVECSKYH GQLTKEAAMGQGFDRHLFAL RHLAAAKGIILPELYLDPAY GQINHNVLSTSTLSSPAVNL GGFAPVVSDGFGVGYAVHDN WIGCNVSSYPGRNAREFLQC VEKALEDMFDALEGKSIKS
Specificity	A synthetic peptide corresponding to a sequence within amino acids 420-658 of human CPT2 (NP_000089.1).

Function	Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites. Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Active with medium (C8-C12) and long-chain (C14-C18) acyl-CoA esters.
Protein Name	Carnitine O-Palmitoyltransferase 2 - Mitochondrial Carnitine Palmitoyltransferase Ii Cpt Ii
Database Links	Reactome: R-HSA-1989781 Reactome: R-HSA-200425
Cellular Localisation	Mitochondrion Inner Membrane Peripheral Membrane Protein Matrix Side
Alternative Antibody Names	Anti-Carnitine O-Palmitoyltransferase 2 - Mitochondrial antibody Anti-Carnitine Palmitoyltransferase Ii antibody Anti-Cpt Ii antibody Anti-CPT2 antibody Anti-CPT1 antibody

Information sourced from Uniprot.org