Anti-CPLX3 antibody (STJA0007575)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human CPLX3
General Information
| Short Description | Rabbit polyclonal anti-Complexin-3 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CPLX3 |
| Gene ID | 594855 |
| Uniprot ID | CPLX3_HUMAN |
| Immunogen | Synthesized peptide derived from human CPLX3 |
| Specificity | This antibody detects endogenous levels of CPLX3 at Human, Mouse |
Additional Info
| Function | Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion. Required for the maintenance of synaptic ultrastructure in the adult retina. Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina. Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release. |
| Protein Name | Complexin-3Complexin IiiCpx Iii |
| Database Links | |
| Cellular Localisation | SynapseCell MembraneLipid-AnchorEnriched At The Synaptic TerminalLocalized At Glycinergic Synaptic Contacts Of Aii Amacrine Cells With Off Cone Bipolar Cells In The Off Sublamina Of The Retina Inner Nuclear Layer |
| Alternative Antibody Names | Anti-Complexin-3 antibodyAnti-Complexin Iii antibodyAnti-Cpx Iii antibodyAnti-CPLX3 antibodyAnti-Nbla11589 antibody |
Information sourced from Uniprot.org