| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Complexin-3 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CPLX3 |
| Gene ID: |
594855 |
| Uniprot ID: |
CPLX3_HUMAN |
| Specificity: |
This antibody detects endogenous levels of CPLX3 at Human, Mouse |
| Immunogen: |
Synthesized peptide derived from human CPLX3 |
| Function | Complexin that regulates SNARE protein complex-mediated synaptic vesicle fusion. Required for the maintenance of synaptic ultrastructure in the adult retina. Positively regulates synaptic transmission through synaptic vesicle availability and exocytosis of neurotransmitters at photoreceptor ribbon synapses in the retina. Suppresses tonic photoreceptor activity and baseline 'noise' by suppression of Ca(2+) vesicle tonic release and the facilitation of evoked synchronous and asynchronous Ca(2+) vesicle release. |
| Protein Name | Complexin-3Complexin IiiCpx Iii |
| Cellular Localisation | SynapseCell MembraneLipid-AnchorEnriched At The Synaptic TerminalLocalized At Glycinergic Synaptic Contacts Of Aii Amacrine Cells With Off Cone Bipolar Cells In The Off Sublamina Of The Retina Inner Nuclear Layer |
| Alternative Antibody Names | Anti-Complexin-3 antibodyAnti-Complexin Iii antibodyAnti-Cpx Iii antibodyAnti-CPLX3 antibodyAnti-Nbla11589 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
