Anti-CPI-17/PPP1R14A antibody (1-147aa) [4H10] (STJA0041533)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2ak
ImmunogenRecombinant human PPP1R14A (1-147aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-CPI-17/PPP1R14A (1-147aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 4H10 |
| Isotype | IgG2ak |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-G affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | PPP1R14A |
| Gene ID | 94274 |
| Uniprot ID | PP14A_HUMAN |
| Accession Number | NP_150281 |
| Immunogen | Recombinant human PPP1R14A (1-147aa) purified from E. coli |
| Immunogen Region | 1-147aa |
Additional Info
| Tissue Specificity | Isoform 1 is detected in aorta and testis. Isoform 2 is detected in aorta. |
| Function | Inhibitor of PPP1CA. Has over 1000-fold higher inhibitory activity when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction. |
| Protein Name | Protein Phosphatase 1 Regulatory Subunit 14a17 Kda Pkc-Potentiated Inhibitory Protein Of Pp1Protein Kinase C-Potentiated Inhibitor Protein Of 17 KdaCpi-17 |
| Database Links | Reactome: R-HSA-5625740 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Protein Phosphatase 1 Regulatory Subunit 14a antibodyAnti-17 Kda Pkc-Potentiated Inhibitory Protein Of Pp1 antibodyAnti-Protein Kinase C-Potentiated Inhibitor Protein Of 17 Kda antibodyAnti-Cpi-17 antibodyAnti-PPP1R14A antibodyAnti-CPI17 antibodyAnti-PPP1INL antibody |
Information sourced from Uniprot.org