Anti-Cone-rod homeobox antibody (Internal) (STJ73027)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-Cone-rod homeobox (Internal) is suitable for use in ELISA, Western Blot and Immunohistochemistry research applications. |
| Applications | Pep-ELISA/WB/IHC |
| Host | Goat |
| Reactivity | Human/Mouse/Rat/Pig/Cow |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:128000.WB: Approx 30kDa band observed in Rat Retina lysates (calculated MW of 32.3kDa according to Human NP_000545.1 and to Rat NP_068627.1). Recommended concentration: 1-3µg/ml. Primary incubat |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20°C on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | CRX |
| Gene ID | 1406 |
| Uniprot ID | CRX_HUMAN |
| Accession Number | NP_000545.1 |
| Immunogen Region | Internal |
| Immunogen Sequence | DPLDYKDQSAWK |
Additional Info
| Function | Transcription factor that binds and transactivates the sequence 5'-TAATCCA-3' which is found upstream of several photoreceptor-specific genes, including the opsin genes. Acts synergistically with other transcription factors, such as NRL, RORB and RAX, to regulate photoreceptor cell-specific gene transcription. Essential for the maintenance of mammalian photoreceptors. |
| Protein Name | Cone-Rod Homeobox Protein |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Cone-Rod Homeobox Protein antibodyAnti-CRX antibodyAnti-CORD2 antibody |
Information sourced from Uniprot.org