![Anti-COL1A1 nanobody [SAA1295] (STJN000085)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/200698/412880/STJN000085-SDS-PAGE-1__60764.1749232422.jpg?c=1 "Anti-COL1A1 nanobody [SAA1295] (STJN000085)")
![Anti-COL1A1 nanobody [SAA1295] (STJN000085)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/200698/412880/STJN000085-SDS-PAGE-1__60764.1749232422.jpg?c=1 "Anti-COL1A1 nanobody [SAA1295] (STJN000085)")
| Host: | Alpaca |
| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Alpaca monoclonal nanobody anti-Collagen Alpha-1 (I Chain is suitable for use in ELISA research applications. |
| Clonality : | Monoclonal |
| Clone ID : | SAA1295 |
| Conjugation: | Unconjugated |
| Isotype: | VHH-8His-Cys-tag |
| Formulation: | 0.01M PBS, pH 7.4. |
| Purification: | Purified by Nickel column. |
| Concentration: | 1 mg/mL |
| Storage Instruction: | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term. |
| Gene Symbol: | COL1A1 |
| Gene ID: | 1277 |
| Uniprot ID: | CO1A1_HUMAN |
| Post Translational Modifications | Contains mostly 4-hydroxyproline. Proline residues at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. Contains 3-hydroxyproline at a few sites. This modification occurs on the first proline residue in the sequence motif Gly-Pro-Hyp, where Hyp is 4-hydroxyproline. Lysine residues at the third position of the tripeptide repeating unit (G-X-Y) are 5-hydroxylated in some or all of the chains. O-glycosylated on hydroxylated lysine residues. The O-linked glycan consists of a Glc-Gal disaccharide. |
| Function | Type I collagen is a member of group I collagen (fibrillar forming collagen). |
| Protein Name | Collagen Alpha-1(I ChainAlpha-1 Type I Collagen |
| Database Links | Reactome: R-HSA-114604Reactome: R-HSA-1442490Reactome: R-HSA-1474244Reactome: R-HSA-1650814Reactome: R-HSA-198933Reactome: R-HSA-2022090Reactome: R-HSA-202733Reactome: R-HSA-216083Reactome: R-HSA-2214320Reactome: R-HSA-2243919Reactome: R-HSA-3000170Reactome: R-HSA-3000171Reactome: R-HSA-3000178Reactome: R-HSA-3000480Reactome: R-HSA-430116Reactome: R-HSA-75892Reactome: R-HSA-76009Reactome: R-HSA-8874081Reactome: R-HSA-8940973Reactome: R-HSA-8948216Reactome: R-HSA-9845619Reactome: R-HSA-9845620Reactome: R-HSA-9845621Reactome: R-HSA-9845622Reactome: R-HSA-9846298 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Nanobody Names | Anti-Collagen Alpha-1(I Chain nanobodyAnti-Alpha-1 Type I Collagen nanobodyAnti-COL1A1 nanobody |
Information sourced from Uniprot.org
