Anti-COL1A1 nanobody [SAA1295] (STJN000085)

SPECIFICATIONS
ClonalityMonoclonal
HostAlpaca
ConjugationUnconjugated
IsotypeVHH-8His-Cys-tag
STJN000085
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General Information

Short DescriptionAlpaca monoclonal nanobody anti-Collagen Alpha-1 (I Chain is suitable for use in ELISA research applications.
ApplicationsELISA
HostAlpaca
ReactivityHuman
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDSAA1295
IsotypeVHH-8His-Cys-tag
ConjugationUnconjugated
Concentration1 mg/mL
PurificationPurified by Nickel column.
Formulation0.01M PBS, pH 7.4.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at-20°C 12 months. Store at-80°C long term.

Target Information

Gene SymbolCOL1A1
Gene ID1277
Uniprot IDCO1A1_HUMAN

Additional Info

Post Translational Modifications Contains mostly 4-hydroxyproline. Proline residues at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. Contains 3-hydroxyproline at a few sites. This modification occurs on the first proline residue in the sequence motif Gly-Pro-Hyp, where Hyp is 4-hydroxyproline. Lysine residues at the third position of the tripeptide repeating unit (G-X-Y) are 5-hydroxylated in some or all of the chains. O-glycosylated on hydroxylated lysine residues. The O-linked glycan consists of a Glc-Gal disaccharide.
Function Type I collagen is a member of group I collagen (fibrillar forming collagen).
Protein Name Collagen Alpha-1(I Chain
Alpha-1 Type I Collagen
Database Links Reactome: R-HSA-114604
Reactome: R-HSA-1442490
Reactome: R-HSA-1474244
Reactome: R-HSA-1650814
Reactome: R-HSA-198933
Reactome: R-HSA-2022090
Reactome: R-HSA-202733
Reactome: R-HSA-216083
Reactome: R-HSA-2214320
Reactome: R-HSA-2243919
Reactome: R-HSA-3000170
Reactome: R-HSA-3000171
Reactome: R-HSA-3000178
Reactome: R-HSA-3000480
Reactome: R-HSA-430116
Reactome: R-HSA-75892
Reactome: R-HSA-76009
Reactome: R-HSA-8874081
Reactome: R-HSA-8940973
Reactome: R-HSA-8948216
Reactome: R-HSA-9845619
Reactome: R-HSA-9845620
Reactome: R-HSA-9845621
Reactome: R-HSA-9845622
Reactome: R-HSA-9846298
Cellular Localisation Secreted
Extracellular Space
Extracellular Matrix
Alternative Nanobody Names Anti-Collagen Alpha-1(I Chain nanobody
Anti-Alpha-1 Type I Collagen nanobody
Anti-COL1A1 nanobody

Information sourced from Uniprot.org

Citations

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