Anti-COL11A1 antibody (260-430) (STJ118005)

Name: Anti-COL11A1 antibody (260-430) (STJ118005)
SKU: STJ118005
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⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ118005

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Short Description	Rabbit polyclonal COL11A1 (260-430) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IHC-P/ELISA
Host	Rabbit
Reactivity	Human/Mouse/Rat
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:1000-1:5000 IHC-P:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	COL11A1
Gene ID	1301
Uniprot ID	COBA1_HUMAN
Immunogen Region	260-430
Immunogen Sequence	EKKKSNFKKKMRTVATKSKE KSKKFTPPKSEKFSSKKKKS YQASAKAKLGVKANIVDDFQ EYNYGTMESYQTEAPRHVSG TNEPNPVEEIFTEEYLTGED YDSQRKNSEDTLYENKEIDG RDSDLLVDGDLGEYDFYEYK EYEDKPTSPPNEEFGPGVPA ETDITETSING
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 260-430 of human COL11A1 (NP_542196.2).

Tissue Specificity	Cartilage, placenta and some tumor or virally transformed cell lines. Isoforms using exon IIA or IIB are found in the cartilage while isoforms using only exon IIB are found in the tendon.
Post Translational Modifications	Prolines at the third position of the tripeptide repeating unit (G-X-Y) are hydroxylated in some or all of the chains. N-glycosylated.
Function	May play an important role in fibrillogenesis by controlling lateral growth of collagen II fibrils.
Protein Name	Collagen Alpha-1(Xi Chain
Database Links	Reactome: R-HSA-1442490 Reactome: R-HSA-1650814 Reactome: R-HSA-2022090 Reactome: R-HSA-3000171 Reactome: R-HSA-8874081 Reactome: R-HSA-8948216
Cellular Localisation	Secreted Extracellular Space Extracellular Matrix
Alternative Antibody Names	Anti-Collagen Alpha-1(Xi Chain antibody Anti-COL11A1 antibody Anti-COLL6 antibody

Information sourced from Uniprot.org