Host: |
Rabbit |
Applications: |
WB |
Reactivity: |
Human |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-CNTN4 (448-697) is suitable for use in Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
Purification: |
Affinity purification |
Dilution Range: |
WB 1:500-1:2000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CNTN4 |
Gene ID: |
152330 |
Uniprot ID: |
CNTN4_HUMAN |
Immunogen Region: |
448-697 |
Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 448-697 of human CNTN4 (NP_001193885.1). |
Immunogen Sequence: |
VGVFNNKGEGPFSPTTVVYS AEEEPTKPPASIFARSLSAT DIEVFWASPLEKNRGRIQGY EVKYWRHEDKEENARKIRTV GNQTSTKITNLKGSVLYHLA VKAYNSAGTGPSSATVNVTT RKPPPSQPPGNIIWNSSDSK IILNWDQVKALDNESEVKGY KVLYRWNRQSSTSVIETNKT SVELSLPFDEDYIIEIKPFS DGGDGSSSEQIRIPKISNAY ARGSGASTSNACTLSAIST |
Tissue Specificity | Mainly expressed in brain. Highly expressed in cerebellum and weakly expressed in corpus callosum, caudate nucleus, amygdala and spinal cord. Also expressed in testis, pancreas, thyroid, uterus, small intestine and kidney. Not expressed in skeletal muscle. Isoform 2 is weakly expressed in cerebral cortex. |
Function | Contactins mediate cell surface interactions during nervous system development. Has some neurite outgrowth-promoting activity. May be involved in synaptogenesis. |
Protein Name | Contactin-4Brain-Derived Immunoglobulin Superfamily Protein 2Big-2 |
Database Links | Reactome: R-HSA-163125 |
Cellular Localisation | Cell MembraneLipid-AnchorGpi-AnchorSecreted |
Alternative Antibody Names | Anti-Contactin-4 antibodyAnti-Brain-Derived Immunoglobulin Superfamily Protein 2 antibodyAnti-Big-2 antibodyAnti-CNTN4 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance