Anti-CNR2 antibody (191-240 aa) (STJ92053)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CNR2 at the amino acid range 191-240
General Information
| Short Description | Rabbit polyclonal anti-Cannabinoid receptor 2 (191-240 aa) for use in WB, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IF 1:200-1:1000ELISA 1:5000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CNR2 |
| Gene ID | 1269 |
| Uniprot ID | CNR2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CNR2 at the amino acid range 191-240 |
| Immunogen Region | 191-240 aa |
| Specificity | CB2 Polyclonal Antibody detects endogenous levels of CB2 protein. |
Additional Info
| Post Translational Modifications | Constitutively phosphorylated on Ser-352.phosphorylation increases cell internalization and desensitizes the receptor. |
| Function | Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis. |
| Protein Name | Cannabinoid Receptor 2Cb-2Cb2Hcb2Cx5 |
| Database Links | Reactome: R-HSA-373076Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionDendritePerikaryonLocalizes To Apical Dendrite Of Pyramidal Neurons |
| Alternative Antibody Names | Anti-Cannabinoid Receptor 2 antibodyAnti-Cb-2 antibodyAnti-Cb2 antibodyAnti-Hcb2 antibodyAnti-Cx5 antibodyAnti-CNR2 antibodyAnti-CB2A antibodyAnti-CB2B antibody |
Information sourced from Uniprot.org