Host: |
Rabbit |
Applications: |
WB/IF/ELISA |
Reactivity: |
Human/Rat/Mouse |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-Cannabinoid receptor 2 (191-240 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: |
1 mg/mL |
Dilution Range: |
WB 1:500-1:2000IF 1:200-1:1000ELISA 1:5000 |
Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Gene Symbol: |
CNR2 |
Gene ID: |
1269 |
Uniprot ID: |
CNR2_HUMAN |
Immunogen Region: |
191-240 aa |
Specificity: |
CB2 Polyclonal Antibody detects endogenous levels of CB2 protein. |
Immunogen: |
The antiserum was produced against synthesized peptide derived from the human CNR2 at the amino acid range 191-240 |
Post Translational Modifications | Constitutively phosphorylated on Ser-352.phosphorylation increases cell internalization and desensitizes the receptor. |
Function | Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis. |
Protein Name | Cannabinoid Receptor 2Cb-2Cb2Hcb2Cx5 |
Database Links | Reactome: R-HSA-373076Reactome: R-HSA-418594 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionDendritePerikaryonLocalizes To Apical Dendrite Of Pyramidal Neurons |
Alternative Antibody Names | Anti-Cannabinoid Receptor 2 antibodyAnti-Cb-2 antibodyAnti-Cb2 antibodyAnti-Hcb2 antibodyAnti-Cx5 antibodyAnti-CNR2 antibodyAnti-CB2A antibodyAnti-CB2B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance