| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-2 3 Cyclic-Nucleotide 3 Phosphodiesterase (152-421) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CNP |
| Gene ID: |
1267 |
| Uniprot ID: |
CN37_HUMAN |
| Immunogen Region: |
152-421 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 152-421 of human CNPase (NP_149124.3). |
| Immunogen Sequence: |
TAWRLDCAQLKEKNQWQLSA DDLKKLKPGLEKDFLPLYFG WFLTKKSSETLRKAGQVFLE ELGNHKAFKKELRQFVPGDE PREKMDLVTYFGKRPPGVLH CTTKFCDYGKAPGAEEYAQQ DVLKKSYSKAFTLTISALFV TPKTTGARVELSEQQLQLWP SDVDKLSPTDNLPRGSRAHI TLGCAADVEAVQTGLDLLEI LRQEKGGSRGEEVGELSRGK LYSLGNGRWMLTLAKNMEV |
| Function | Catalyzes the formation of 2'-nucleotide products from 2',3'-cyclic substrates. May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin. |
| Protein Name | 2' -3'-Cyclic-Nucleotide 3'-PhosphodiesteraseCnpCnpase |
| Cellular Localisation | MembraneLipid-AnchorMelanosomeFirmly Bound To Membrane Structures Of Brain White Matter |
| Alternative Antibody Names | Anti-2' -3'-Cyclic-Nucleotide 3'-Phosphodiesterase antibodyAnti-Cnp antibodyAnti-Cnpase antibodyAnti-CNP antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
![Western blot analysis of lysates from wild type (WT) and CNPasease knockout (KO) HeLa cells, using [KO Validated] CNPase Rabbit polyclonal antibody (STJ119982) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/300x300/products/98767/382818/STJ119982_1__79726.1713151315.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and CNPasease knockout (KO) HeLa cells, using [KO Validated] CNPase Rabbit polyclonal antibody (STJ119982) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.")
