• Immunohistochemical analysis of paraffin-embedded human Small intestinal stromal tumor. 1, Tris-EDTA, pH9.0 was used for antigen retrieval. 2 Antibody was diluted at 1:200 (4°C overnight. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-CMYA5 antibody (3866-3916 aa) (STJ196582)

SKU:
STJ196582

£46.00 - £226.00
Current Stock:
Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cardiomyopathy-associated protein 5 (3866-3916 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-200
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CMYA5
Gene ID: 202333
Uniprot ID: CMYA5_HUMAN
Immunogen Region: 3866-3916 aa
Specificity: This antibody detects endogenous levels of CMYA5 at Human/Mouse
Immunogen: Synthesized peptide derived from the human CMYA5 at the amino acid range 3866-3916
Post Translational Modifications Phosphorylated by PKA.
Function May serve as an anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) via binding to PRKAR2A. May function as a repressor of calcineurin-mediated transcriptional activity. May attenuate calcineurin ability to induce slow-fiber gene program in muscle and may negatively modulate skeletal muscle regeneration. Plays a role in the assembly of ryanodine receptor (RYR2) clusters in striated muscle.
Protein Name Cardiomyopathy-Associated Protein 5
Dystrobrevin-Binding Protein 2
Genethonin-3
Myospryn
Spry Domain-Containing Protein 2
Tripartite Motif-Containing Protein 76
Cellular Localisation Nucleus
Sarcoplasmic Reticulum
Cytoplasm
Perinuclear Region
Myofibril
Sarcomere
M Line
Found Predominantly At The Periphery Of The Nucleus But Also Throughout The Cell
Localized In Lysosomes
In Skeletal Muscles
Localizes Along Myofiber Periphery
At Costameres
Predominantly Flanks Z-Disks
Occasionally Present At The M-Band Level
Colocalized With Ryr2 In The Sarcoplasmic Reticulum
Alternative Antibody Names Anti-Cardiomyopathy-Associated Protein 5 antibody
Anti-Dystrobrevin-Binding Protein 2 antibody
Anti-Genethonin-3 antibody
Anti-Myospryn antibody
Anti-Spry Domain-Containing Protein 2 antibody
Anti-Tripartite Motif-Containing Protein 76 antibody
Anti-CMYA5 antibody
Anti-C5orf10 antibody
Anti-DTNBP2 antibody
Anti-SPRYD2 antibody
Anti-TRIM76 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance