Post Translational Modifications | Phosphorylated by PKA. |
Function | May serve as an anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) via binding to PRKAR2A. May function as a repressor of calcineurin-mediated transcriptional activity. May attenuate calcineurin ability to induce slow-fiber gene program in muscle and may negatively modulate skeletal muscle regeneration. Plays a role in the assembly of ryanodine receptor (RYR2) clusters in striated muscle. |
Protein Name | Cardiomyopathy-Associated Protein 5Dystrobrevin-Binding Protein 2Genethonin-3MyosprynSpry Domain-Containing Protein 2Tripartite Motif-Containing Protein 76 |
Cellular Localisation | NucleusSarcoplasmic ReticulumCytoplasmPerinuclear RegionMyofibrilSarcomereM LineFound Predominantly At The Periphery Of The Nucleus But Also Throughout The CellLocalized In LysosomesIn Skeletal MusclesLocalizes Along Myofiber PeripheryAt CostameresPredominantly Flanks Z-DisksOccasionally Present At The M-Band LevelColocalized With Ryr2 In The Sarcoplasmic Reticulum |
Alternative Antibody Names | Anti-Cardiomyopathy-Associated Protein 5 antibodyAnti-Dystrobrevin-Binding Protein 2 antibodyAnti-Genethonin-3 antibodyAnti-Myospryn antibodyAnti-Spry Domain-Containing Protein 2 antibodyAnti-Tripartite Motif-Containing Protein 76 antibodyAnti-CMYA5 antibodyAnti-C5orf10 antibodyAnti-DTNBP2 antibodyAnti-SPRYD2 antibodyAnti-TRIM76 antibody |
Information sourced from Uniprot.org