| Host: |
Rabbit |
| Applications: |
IHC/IF |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Cardiomyopathy-associated protein 5 (3866-3916 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
IHC-P 1:50-200IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CMYA5 |
| Gene ID: |
202333 |
| Uniprot ID: |
CMYA5_HUMAN |
| Immunogen Region: |
3866-3916 aa |
| Specificity: |
This antibody detects endogenous levels of CMYA5 at Human/Mouse |
| Immunogen: |
Synthesized peptide derived from the human CMYA5 at the amino acid range 3866-3916 |
| Post Translational Modifications | Phosphorylated by PKA. |
| Function | May serve as an anchoring protein that mediates the subcellular compartmentation of protein kinase A (PKA) via binding to PRKAR2A. May function as a repressor of calcineurin-mediated transcriptional activity. May attenuate calcineurin ability to induce slow-fiber gene program in muscle and may negatively modulate skeletal muscle regeneration. Plays a role in the assembly of ryanodine receptor (RYR2) clusters in striated muscle. |
| Protein Name | Cardiomyopathy-Associated Protein 5Dystrobrevin-Binding Protein 2Genethonin-3MyosprynSpry Domain-Containing Protein 2Tripartite Motif-Containing Protein 76 |
| Cellular Localisation | NucleusSarcoplasmic ReticulumCytoplasmPerinuclear RegionMyofibrilSarcomereM LineFound Predominantly At The Periphery Of The Nucleus But Also Throughout The CellLocalized In LysosomesIn Skeletal MusclesLocalizes Along Myofiber PeripheryAt CostameresPredominantly Flanks Z-DisksOccasionally Present At The M-Band LevelColocalized With Ryr2 In The Sarcoplasmic Reticulum |
| Alternative Antibody Names | Anti-Cardiomyopathy-Associated Protein 5 antibodyAnti-Dystrobrevin-Binding Protein 2 antibodyAnti-Genethonin-3 antibodyAnti-Myospryn antibodyAnti-Spry Domain-Containing Protein 2 antibodyAnti-Tripartite Motif-Containing Protein 76 antibodyAnti-CMYA5 antibodyAnti-C5orf10 antibodyAnti-DTNBP2 antibodyAnti-SPRYD2 antibodyAnti-TRIM76 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
