Anti-CLUH antibody (1120-1309) (STJ112179)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CLUH (1120-1309) antibody for use in WB, IHC-P, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:1000-1:4000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CLUH |
| Gene ID | 23277 |
| Uniprot ID | CLU_HUMAN |
| Immunogen Region | 1120-1309 |
| Immunogen Sequence | YDLSLRFLENALAVSTKYHG PKALKVALSHHLVARVYESK AEFRSALQHEKEGYTIYKTQ LGEDHEKTKESSEYLKCLTQ QAVALQRTMNEIYRNGSSAN IPPLKFTAPSMASVLEQLNV INGILFIPLSQKDLENLKAE VARRHQLQEASRNRDRAEEP MATEPAPAGAPGDLGSQPPA AKDPSPSVQG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1120-1309 of human CLUH (NP_056044.3). |
Additional Info
| Function | mRNA-binding protein involved in proper cytoplasmic distribution of mitochondria. Specifically binds mRNAs of nuclear-encoded mitochondrial proteins in the cytoplasm and regulates transport or translation of these transcripts close to mitochondria, playing a role in mitochondrial biogenesis. |
| Protein Name | Clustered Mitochondria Protein Homolog |
| Database Links | |
| Cellular Localisation | CytoplasmCytoplasmic GranuleA Fraction Colocalizes With Tyrosinated Tubulin And Can Be Detected Close To Mitochondria |
| Alternative Antibody Names | Anti-Clustered Mitochondria Protein Homolog antibodyAnti-CLUH antibodyAnti-KIAA0664 antibody |
Information sourced from Uniprot.org