| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CLEC2D (60-154) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CLEC2D |
| Gene ID: |
29121 |
| Uniprot ID: |
CLC2D_HUMAN |
| Immunogen Region: |
60-154 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 60-154 of human CLEC2D (NP_037401.1). |
| Immunogen Sequence: |
RANCHQEPSVCLQAACPESW IGFQRKCFYFSDDTKNWTSS QRFCDSQDADLAQVESFQEL NFLLRYKGPSDHWIGLSREQ GQPWKWINGTEWTRQ |
| Tissue Specificity | Detected in peripheral blood leukocytes, osteoblasts, lymph node, thymus and spleen. Isoform 1, isoform 2 and isoform 4 are expressed in T- and B-lymphocytes, and at lower levels in NK cells. They are also expressed in B-cell lines and LPS-matured monocyte-derived dendritic cells. |
| Post Translational Modifications | N-glycosylated. |
| Function | Receptor for KLRB1 that protects target cells against natural killer cell-mediated lysis. Inhibits osteoclast formation. Inhibits bone resorption. Modulates the release of interferon-gamma. Binds high molecular weight sulfated glycosaminoglycans. |
| Protein Name | C-Type Lectin Domain Family 2 Member DLectin-Like Nk Cell ReceptorLectin-Like Transcript 1Llt-1Osteoclast Inhibitory Lectin |
| Database Links | Reactome: R-HSA-198933 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinIsoform 2: Endoplasmic ReticulumIsoform 4: Endoplasmic Reticulum |
| Alternative Antibody Names | Anti-C-Type Lectin Domain Family 2 Member D antibodyAnti-Lectin-Like Nk Cell Receptor antibodyAnti-Lectin-Like Transcript 1 antibodyAnti-Llt-1 antibodyAnti-Osteoclast Inhibitory Lectin antibodyAnti-CLEC2D antibodyAnti-CLAX antibodyAnti-LLT1 antibodyAnti-OCIL antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
