• STJ71857 (2µg/ml) staining of Human Liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-CLEC16A antibody (1040-53) (STJ71857)

SKU:
STJ71857-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-CLEC16A (1040-53) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-1-3µg/ml
ELISA-antibody detection limit dilution 1:1000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: CLEC16A
Gene ID: 23274
Uniprot ID: CL16A_HUMAN
Immunogen Region: 1040-53
Accession Number: NP_056041.1
Immunogen Sequence: EEAACAEPVGTAED
Function Regulator of mitophagy through the upstream regulation of the RNF41/NRDP1-PRKN pathway. Mitophagy is a selective form of autophagy necessary for mitochondrial quality control. The RNF41/NRDP1-PRKN pathway regulates autophagosome-lysosome fusion during late mitophagy. May protect RNF41/NRDP1 from proteasomal degradation, RNF41/NRDP1 which regulates proteasomal degradation of PRKN. Plays a key role in beta cells functions by regulating mitophagy/autophagy and mitochondrial health.
Protein Name Protein Clec16a
C-Type Lectin Domain Family 16 Member A
Cellular Localisation Endosome Membrane
Peripheral Membrane Protein
Lysosome Membrane
Associates With The Endolysosome Membrane
Alternative Antibody Names Anti-Protein Clec16a antibody
Anti-C-Type Lectin Domain Family 16 Member A antibody
Anti-CLEC16A antibody
Anti-KIAA0350 antibody

Information sourced from Uniprot.org

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