| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CLEC11A |
| Gene ID: | 6320 |
| Uniprot ID: | CLC11_HUMAN |
| Immunogen Region: | 22-323 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-323 of human CLEC11A (NP_002966.1). |
| Immunogen Sequence: | ARGAEREWEGGWGGAQEEER EREALMLKHLQEALGLPAGR GDENPAGTVEGKEDWEMEED QGEEEEEEATPTPSSGPSPS PTPEDIVTYILGRLAGLDAG LHQLHVRLHALDTRVVELTQ GLRQLRNAAGDTRDAVQALQ EAQGRAEREHGRLEGCLKGL RLGHKCFLLSRDFEAQAAAQ ARCTARGGSLAQPADRQQME ALTRYLRAALAPYNWPVWLG VHDRRAEGLYLFENGQRVS |
| Tissue Specificity | Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver. |
| Post Translational Modifications | O-glycosylated. Probably sulfated on the O-glycans. |
| Function | Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts. Important for repair and maintenance of adult bone. |
| Protein Name | C-Type Lectin Domain Family 11 Member AC-Type Lectin Superfamily Member 3Lymphocyte Secreted C-Type LectinOsteolectinStem Cell Growth FactorP47 |
| Cellular Localisation | CytoplasmSecreted |
| Alternative Antibody Names | Anti-C-Type Lectin Domain Family 11 Member A antibodyAnti-C-Type Lectin Superfamily Member 3 antibodyAnti-Lymphocyte Secreted C-Type Lectin antibodyAnti-Osteolectin antibodyAnti-Stem Cell Growth Factor antibodyAnti-P47 antibodyAnti-CLEC11A antibodyAnti-CLECSF3 antibodyAnti-LSLCL antibodyAnti-SCGF antibody |
Information sourced from Uniprot.org