Anti-CLEC11A antibody (22-323) (STJ25448)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CLEC11A (22-323) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CLEC11A |
| Gene ID | 6320 |
| Uniprot ID | CLC11_HUMAN |
| Immunogen Region | 22-323 |
| Immunogen Sequence | ARGAEREWEGGWGGAQEEER EREALMLKHLQEALGLPAGR GDENPAGTVEGKEDWEMEED QGEEEEEEATPTPSSGPSPS PTPEDIVTYILGRLAGLDAG LHQLHVRLHALDTRVVELTQ GLRQLRNAAGDTRDAVQALQ EAQGRAEREHGRLEGCLKGL RLGHKCFLLSRDFEAQAAAQ ARCTARGGSLAQPADRQQME ALTRYLRAALAPYNWPVWLG VHDRRAEGLYLFENGQRVS |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 22-323 of human CLEC11A (NP_002966.1). |
Additional Info
| Tissue Specificity | Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver. |
| Post Translational Modifications | O-glycosylated. Probably sulfated on the O-glycans. |
| Function | Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts. Important for repair and maintenance of adult bone. |
| Protein Name | C-Type Lectin Domain Family 11 Member AC-Type Lectin Superfamily Member 3Lymphocyte Secreted C-Type LectinOsteolectinStem Cell Growth FactorP47 |
| Database Links | |
| Cellular Localisation | CytoplasmSecreted |
| Alternative Antibody Names | Anti-C-Type Lectin Domain Family 11 Member A antibodyAnti-C-Type Lectin Superfamily Member 3 antibodyAnti-Lymphocyte Secreted C-Type Lectin antibodyAnti-Osteolectin antibodyAnti-Stem Cell Growth Factor antibodyAnti-P47 antibodyAnti-CLEC11A antibodyAnti-CLECSF3 antibodyAnti-LSLCL antibodyAnti-SCGF antibody |
Information sourced from Uniprot.org