Anti-Cleaved-F2RL3-G48 antibody (29-78 aa) (STJ90071)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human PAR4 at the amino acid range 29-78
General Information
| Short Description | Rabbit polyclonal anti-Cleaved-Proteinase-activated receptor 4-G48 (29-78 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:5000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | F2RL3 |
| Gene ID | 9002 |
| Uniprot ID | PAR4_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human PAR4 at the amino acid range 29-78 |
| Immunogen Region | 29-78 aa |
| Specificity | Cleaved-PAR-4 (G48) Polyclonal Antibody detects endogenous levels of fragment of activated PAR-4 protein resulting from cleavage adjacent to G48. |
Additional Info
| Post Translational Modifications | A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand. |
| Function | Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation. |
| Protein Name | Proteinase-Activated Receptor 4Par-4Coagulation Factor Ii Receptor-Like 3Thrombin Receptor-Like 3 |
| Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476Reactome: R-HSA-456926 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Proteinase-Activated Receptor 4 antibodyAnti-Par-4 antibodyAnti-Coagulation Factor Ii Receptor-Like 3 antibodyAnti-Thrombin Receptor-Like 3 antibodyAnti-F2RL3 antibodyAnti-PAR4 antibody |
Information sourced from Uniprot.org