• Western blot analysis of lysates from NIH/3T3 cells, treated with etoposide 25uM 1h, using PAR4 (Cleaved-Gly48) Antibody. The lane on the right is blocked with the synthesized peptide.
  • Western blot analysis of NIH-3T3 cells using Cleaved-PAR-4 (G48) Polyclonal Antibody

Anti-Cleaved-F2RL3-G48 antibody (29-78 aa) (STJ90071)

SKU:
STJ90071

€57.50 - €282.50
Current Stock:
Host: Rabbit
Applications: WB/ELISA
Reactivity: Human/Rat/Mouse
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Cleaved-Proteinase-activated receptor 4-G48 (29-78 aa) is suitable for use in Western Blot and ELISA research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-1:2000
ELISA 1:5000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: F2RL3
Gene ID: 9002
Uniprot ID: PAR4_HUMAN
Immunogen Region: 29-78 aa
Specificity: Cleaved-PAR-4 (G48) Polyclonal Antibody detects endogenous levels of fragment of activated PAR-4 protein resulting from cleavage adjacent to G48.
Immunogen: The antiserum was produced against synthesized peptide derived from the human PAR4 at the amino acid range 29-78
Post Translational Modifications A proteolytic cleavage generates a new N-terminus that functions as a tethered ligand.
Function Receptor for activated thrombin or trypsin coupled to G proteins that stimulate phosphoinositide hydrolysis. May play a role in platelets activation.
Protein Name Proteinase-Activated Receptor 4
Par-4
Coagulation Factor Ii Receptor-Like 3
Thrombin Receptor-Like 3
Database Links Reactome: R-HSA-375276
Reactome: R-HSA-416476
Reactome: R-HSA-456926
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Proteinase-Activated Receptor 4 antibody
Anti-Par-4 antibody
Anti-Coagulation Factor Ii Receptor-Like 3 antibody
Anti-Thrombin Receptor-Like 3 antibody
Anti-F2RL3 antibody
Anti-PAR4 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance