| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CHRD |
| Gene ID: | 8646 |
| Uniprot ID: | CHRD_HUMAN |
| Immunogen Region: | 686-955 |
| Immunogen Sequence: | PALAPAKPGGPGRPRDPNTC FFEGQQRPHGARWAPNYDPL CSLCTCQRRTVICDPVVCPP PSCPHPVQAPDQCCPVCPEK QDVRDLPGLPRSRDPGEGCY FDGDRSWRAAGTRWHPVVPP FGLIKCAVCTCKGGTGEVHC EKVQCPRLACAQPVRVNPTD CCKQCPVGSGAHPQLGDPMQ ADGPRGCRFAGQWFPESQSW HPSVPPFGEMSCITCRCGAG VPHCERDDCSLPLSCGSGK |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 686-955 of human CHRD (NP_003732.2). |
| Tissue Specificity | Expressed at the highest level in liver. |
| Post Translational Modifications | Cleaved by tolloid proteases.cleavage participates in dorsoventral patterning during early development. |
| Function | Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. |
| Protein Name | Chordin |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Chordin antibodyAnti-CHRD antibodyAnti-UNQ217 antibodyAnti-PRO243 antibody |
Information sourced from Uniprot.org
