| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CHRD (686-955) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CHRD |
| Gene ID: |
8646 |
| Uniprot ID: |
CHRD_HUMAN |
| Immunogen Region: |
686-955 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 686-955 of human CHRD (NP_003732.2). |
| Immunogen Sequence: |
PALAPAKPGGPGRPRDPNTC FFEGQQRPHGARWAPNYDPL CSLCTCQRRTVICDPVVCPP PSCPHPVQAPDQCCPVCPEK QDVRDLPGLPRSRDPGEGCY FDGDRSWRAAGTRWHPVVPP FGLIKCAVCTCKGGTGEVHC EKVQCPRLACAQPVRVNPTD CCKQCPVGSGAHPQLGDPMQ ADGPRGCRFAGQWFPESQSW HPSVPPFGEMSCITCRCGAG VPHCERDDCSLPLSCGSGK |
| Tissue Specificity | Expressed at the highest level in liver. |
| Post Translational Modifications | Cleaved by tolloid proteases.cleavage participates in dorsoventral patterning during early development. |
| Function | Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. |
| Protein Name | Chordin |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Chordin antibodyAnti-CHRD antibodyAnti-UNQ217 antibodyAnti-PRO243 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
