Anti-CHRD antibody (686-955) (STJ119644)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CHRD (686-955) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CHRD |
| Gene ID | 8646 |
| Uniprot ID | CHRD_HUMAN |
| Immunogen Region | 686-955 |
| Immunogen Sequence | PALAPAKPGGPGRPRDPNTC FFEGQQRPHGARWAPNYDPL CSLCTCQRRTVICDPVVCPP PSCPHPVQAPDQCCPVCPEK QDVRDLPGLPRSRDPGEGCY FDGDRSWRAAGTRWHPVVPP FGLIKCAVCTCKGGTGEVHC EKVQCPRLACAQPVRVNPTD CCKQCPVGSGAHPQLGDPMQ ADGPRGCRFAGQWFPESQSW HPSVPPFGEMSCITCRCGAG VPHCERDDCSLPLSCGSGK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 686-955 of human CHRD (NP_003732.2). |
Additional Info
| Tissue Specificity | Expressed at the highest level in liver. |
| Post Translational Modifications | Cleaved by tolloid proteases.cleavage participates in dorsoventral patterning during early development. |
| Function | Dorsalizing factor. Key developmental protein that dorsalizes early vertebrate embryonic tissues by binding to ventralizing TGF-beta family bone morphogenetic proteins (BMPs) and sequestering them in latent complexes. |
| Protein Name | Chordin |
| Database Links | |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Chordin antibodyAnti-CHRD antibodyAnti-UNQ217 antibodyAnti-PRO243 antibody |
Information sourced from Uniprot.org