Anti-CHPF antibody (631-680 aa) (STJ92289)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human CHSY2 at the amino acid range 631-680
General Information
| Short Description | Rabbit polyclonal anti-Chondroitin sulfate synthase 2 (631-680 aa) for use in WB, IHC, IF and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000IHC 1:100-1:300IF 1:200-1:1000ELISA 1:40000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CHPF |
| Gene ID | 79586 |
| Uniprot ID | CHSS2_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human CHSY2 at the amino acid range 631-680 |
| Immunogen Region | 631-680 aa |
| Specificity | CHSY2 Polyclonal Antibody detects endogenous levels of CHSY2 protein. |
Additional Info
| Function | Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Seems to act as a specific activating factor for CHSY1 in chondroitin polymerization. Isoform 2: May facilitate PRKN transport into the mitochondria. In collaboration with PRKN, may enhance cell viability and protect cells from oxidative stress. |
| Protein Name | Chondroitin Sulfate Synthase 2Chondroitin Glucuronyltransferase 2Chondroitin-Polymerizing FactorChpfGlucuronosyl-N-Acetylgalactosaminyl-Proteoglycan 4-Beta-N-Acetylgalactosaminyltransferase IiN-Acetylgalactosaminyl-Proteoglycan 3-Beta-Glucuronosyltransferase IiN-Acetylgalactosaminyltransferase 2 |
| Database Links | Reactome: R-HSA-2022870 |
| Cellular Localisation | Isoform 1: Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinCytoplasmCytosolIsoform 3: CytoplasmMitochondrionIsoform 2: Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Chondroitin Sulfate Synthase 2 antibodyAnti-Chondroitin Glucuronyltransferase 2 antibodyAnti-Chondroitin-Polymerizing Factor antibodyAnti-Chpf antibodyAnti-Glucuronosyl-N-Acetylgalactosaminyl-Proteoglycan 4-Beta-N-Acetylgalactosaminyltransferase Ii antibodyAnti-N-Acetylgalactosaminyl-Proteoglycan 3-Beta-Glucuronosyltransferase Ii antibodyAnti-N-Acetylgalactosaminyltransferase 2 antibodyAnti-CHPF antibodyAnti-CSS2 antibodyAnti-UNQ651 antibodyAnti-PRO1281 antibody |
Information sourced from Uniprot.org