| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CHD9 |
| Gene ID: | 80205 |
| Uniprot ID: | CHD9_HUMAN |
| Immunogen Region: | 85-190 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 85-190 of human CHD9 (NP_079410.4). |
| Immunogen Sequence: | SFGSPAEHVLSPHSQFNCSP IHPQNQPNGLFPDVSDGSPM WGHQTATTISNQNGSPFHQQ GHSHSMHQNKSFVAHHDFAL FQANEQQTQCTSLRSQQNRN NLNPGQ |
| Tissue Specificity | Widely expressed at low levels. In bone marrow, expression is restricted to osteoprogenitor cells adjacent to mature osteoblasts. |
| Post Translational Modifications | Phosphorylated on serine and tyrosine residues. |
| Function | Acts as a transcriptional coactivator for PPARA and possibly other nuclear receptors. Proposed to be a ATP-dependent chromatin remodeling protein. Has DNA-dependent ATPase activity and binds to A/T-rich DNA. Associates with A/T-rich regulatory regions in promoters of genes that participate in the differentiation of progenitors during osteogenesis. |
| Protein Name | Chromodomain-Helicase-Dna-Binding Protein 9Chd-9Atp-Dependent Helicase Chd9Chromatin-Related Mesenchymal ModulatorCremmChromatin-Remodeling Factor Chrom1Kismet Homolog 2Ppar-Alpha-Interacting Complex Protein 320 KdaPeroxisomal Proliferator-Activated Receptor A-Interacting Complex 320 Kda Protein |
| Database Links | Reactome: R-HSA-1368082Reactome: R-HSA-1368108Reactome: R-HSA-1989781Reactome: R-HSA-2151201Reactome: R-HSA-2426168Reactome: R-HSA-381340Reactome: R-HSA-400206Reactome: R-HSA-400253Reactome: R-HSA-9707564Reactome: R-HSA-9707616 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-Chromodomain-Helicase-Dna-Binding Protein 9 antibodyAnti-Chd-9 antibodyAnti-Atp-Dependent Helicase Chd9 antibodyAnti-Chromatin-Related Mesenchymal Modulator antibodyAnti-Cremm antibodyAnti-Chromatin-Remodeling Factor Chrom1 antibodyAnti-Kismet Homolog 2 antibodyAnti-Ppar-Alpha-Interacting Complex Protein 320 Kda antibodyAnti-Peroxisomal Proliferator-Activated Receptor A-Interacting Complex 320 Kda Protein antibodyAnti-CHD9 antibodyAnti-KIAA0308 antibodyAnti-KISH2 antibodyAnti-PRIC320 antibodyAnti-AD-013 antibodyAnti-x0008 antibody |
Information sourced from Uniprot.org
