| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CHAF1A (1-200) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CHAF1A |
| Gene ID: |
10036 |
| Uniprot ID: |
CAF1A_HUMAN |
| Immunogen Region: |
1-200 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human p150 CAF1 (NP_005474.2). |
| Immunogen Sequence: |
MLEELECGAPGARGAATAMD CKDRPAFPVKKLIQARLPFK RLNLVPKGKADDMSDDQGTS VQSKSPDLEASLDTLENNCH VGSDIDFRPKLVNGKGPLDN FLRNRIETSIGQSTVIIDLT EDSNEQPDSLVDHNKLNSEA SPSREAINGQREDTGDQQGL LKAIQNDKLAFPGETLSDIP CKTEEEGVGCGGAGRRGDSQ |
| Function | Core component of the CAF-1 complex, a complex that is thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA.histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci. |
| Protein Name | Chromatin Assembly Factor 1 Subunit ACaf-1 Subunit AChromatin Assembly Factor I P150 SubunitCaf-I 150 Kda SubunitCaf-I P150Hp150 |
| Cellular Localisation | NucleusDna Replication Foci |
| Alternative Antibody Names | Anti-Chromatin Assembly Factor 1 Subunit A antibodyAnti-Caf-1 Subunit A antibodyAnti-Chromatin Assembly Factor I P150 Subunit antibodyAnti-Caf-I 150 Kda Subunit antibodyAnti-Caf-I P150 antibodyAnti-Hp150 antibodyAnti-CHAF1A antibodyAnti-CAF antibodyAnti-CAF1P150 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
