Anti-CHAF1A antibody (1-200) (STJ117797)

Name: Anti-CHAF1A antibody (1-200) (STJ117797)
SKU: STJ117797
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ117797

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Short Description	Rabbit polyclonal CHAF1A (1-200) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/ELISA
Host	Rabbit
Reactivity	Human
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:2000 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	CHAF1A
Gene ID	10036
Uniprot ID	CAF1A_HUMAN
Immunogen Region	1-200
Immunogen Sequence	MLEELECGAPGARGAATAMD CKDRPAFPVKKLIQARLPFK RLNLVPKGKADDMSDDQGTS VQSKSPDLEASLDTLENNCH VGSDIDFRPKLVNGKGPLDN FLRNRIETSIGQSTVIIDLT EDSNEQPDSLVDHNKLNSEA SPSREAINGQREDTGDQQGL LKAIQNDKLAFPGETLSDIP CKTEEEGVGCGGAGRRGDSQ
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human p150 CAF1 (NP_005474.2).

Function	Acts as a component of the histone chaperone complex chromatin assembly factor 1 (CAF-1), which assembles histone octamers onto DNA during replication and repair. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA.histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci.
Protein Name	Chromatin Assembly Factor 1 Subunit A Caf-1 Subunit A Chromatin Assembly Factor I P150 Subunit Caf-I 150 Kda Subunit Caf-I P150 Hp150
Database Links
Cellular Localisation	Nucleus Dna Replication Foci
Alternative Antibody Names	Anti-Chromatin Assembly Factor 1 Subunit A antibody Anti-Caf-1 Subunit A antibody Anti-Chromatin Assembly Factor I P150 Subunit antibody Anti-Caf-I 150 Kda Subunit antibody Anti-Caf-I P150 antibody Anti-Hp150 antibody Anti-CHAF1A antibody Anti-CAF antibody Anti-CAF1P150 antibody

Information sourced from Uniprot.org