| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CGN (904-1203) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CGN |
| Gene ID: |
57530 |
| Uniprot ID: |
CING_HUMAN |
| Immunogen Region: |
904-1203 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 904-1203 of human CGN (NP_065821.1). |
| Immunogen Sequence: |
TSGGLSRLQDEIQRLRQALQ ASQAERDTARLDKELLAQRL QGLEQEAENKKRSQDDRARQ LKGLEEKVSRLETELDEEKN TVELLTDRVNRGRDQVDQLR TELMQERSARQDLECDKISL ERQNKDLKTRLASSEGFQKP SASLSQLESQNQLLQERLQA EEREKTVLQSTNRKLERKVK ELSIQIEDERQHVNDQKDQL SLRVKALKRQVDEAEEEIER LDGLRKKAQREVEEQHEVN |
| Tissue Specificity | Localized on the cytoplasmic face of tight junctions of polarized epithelia and some endothelia. Expressed in pancreas, kidney, liver and lung, but not in skeletal muscle, placenta, brain or heart. |
| Function | Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. |
| Protein Name | Cingulin |
| Database Links | Reactome: R-HSA-2173791 |
| Cellular Localisation | Cell JunctionTight JunctionLocalizes To The Apical Junction Complex Composed Of Tight And Adherens JunctionsColocalizes With Spef1 At Sites Of Cell-Cell Contact In Intestinal Epithelial Cells |
| Alternative Antibody Names | Anti-Cingulin antibodyAnti-CGN antibodyAnti-KIAA1319 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
