Anti-CGN antibody (904-1203) (STJ117684)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CGN (904-1203) antibody for use in WB, IHC-P and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CGN |
| Gene ID | 57530 |
| Uniprot ID | CING_HUMAN |
| Immunogen Region | 904-1203 |
| Immunogen Sequence | TSGGLSRLQDEIQRLRQALQ ASQAERDTARLDKELLAQRL QGLEQEAENKKRSQDDRARQ LKGLEEKVSRLETELDEEKN TVELLTDRVNRGRDQVDQLR TELMQERSARQDLECDKISL ERQNKDLKTRLASSEGFQKP SASLSQLESQNQLLQERLQA EEREKTVLQSTNRKLERKVK ELSIQIEDERQHVNDQKDQL SLRVKALKRQVDEAEEEIER LDGLRKKAQREVEEQHEVN |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 904-1203 of human CGN (NP_065821.1). |
Additional Info
| Tissue Specificity | Localized on the cytoplasmic face of tight junctions of polarized epithelia and some endothelia. Expressed in pancreas, kidney, liver and lung, but not in skeletal muscle, placenta, brain or heart. |
| Function | Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. |
| Protein Name | Cingulin |
| Database Links | Reactome: R-HSA-2173791 |
| Cellular Localisation | Cell JunctionTight JunctionLocalizes To The Apical Junction Complex Composed Of Tight And Adherens JunctionsColocalizes With Spef1 At Sites Of Cell-Cell Contact In Intestinal Epithelial Cells |
| Alternative Antibody Names | Anti-Cingulin antibodyAnti-CGN antibodyAnti-KIAA1319 antibody |
Information sourced from Uniprot.org