| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Carboxylesterase 3 (447-497 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CES3 |
| Gene ID: |
23491 |
| Uniprot ID: |
EST3_HUMAN |
| Immunogen Region: |
447-497 aa |
| Specificity: |
This antibody detects endogenous levels of EST3 at Human |
| Immunogen: |
Synthesized peptide derived from the human EST3 at the amino acid range 447-497 |
| Post Translational Modifications | N-glycosylated. |
| Function | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-4-(1-piperidino)-1-piperidino-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics. |
| Protein Name | Carboxylesterase 3Liver Carboxylesterase 31 Homolog |
| Database Links | Reactome: R-HSA-211945Reactome: R-HSA-8964038 |
| Cellular Localisation | Endoplasmic Reticulum Lumen |
| Alternative Antibody Names | Anti-Carboxylesterase 3 antibodyAnti-Liver Carboxylesterase 31 Homolog antibodyAnti-CES3 antibodyAnti-UNQ869 antibodyAnti-PRO1887 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
